Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631525 | 0.92 | EDNRA (0.63) | EDNRAEDNRB | |
| SCHEMBL4631825 | 0.89 | EDNRA (0.75) | EDNRAEDNRB | |
| SCHEMBL4632022 | 0.88 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL4631566 | 0.88 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL4660858 | 0.87 | EDNRA (0.62) | EDNRAEDNRB | |
| SCHEMBL4630673 | 0.87 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL4631403 | 0.86 | EDNRA (0.60) | EDNRAEDNRB | |
| SCHEMBL27543155 | 0.86 | EDNRA (0.61) | EDNRAEDNRB | |
| SCHEMBL4631575 | 0.85 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL4631347 | 0.85 | EDNRA (0.61) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001049289-A1 | PHARMACEUTICAL AND VETERINARY USES OF ENDOTHELIN ANTAGONISTS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-07-12 | — | — | WO | claimed |
| CN-1253560-A | Sulfonamides for the treatment of endothelin mediated diseases | TEXA BIOTECHNOLOGY CORP (US) | 2000-05-17 | — | — | CN | claimed |
| WO-2001049289-A1 | PHARMACEUTICAL AND VETERINARY USES OF ENDOTHELIN ANTAGONISTS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-07-12 | — | — | WO | disclosed |
| CN-1253560-A | Sulfonamides for the treatment of endothelin mediated diseases | TEXA BIOTECHNOLOGY CORP (US) | 2000-05-17 | — | — | CN | disclosed |