Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954868 | 0.99 | ELANE (0.56) | ELANEKDM4EOPRK1KMT2AMEN1 | |
| SCHEMBL7966469 | 0.97 | ELANE (0.56) | ELANEKDM4EOPRK1KMT2AMEN1 | |
| SCHEMBL7953666 | 0.95 | ELANE (0.58) | ELANEOPRK1TDP1MAPK1HTR3A | |
| SCHEMBL7966421 | 0.91 | ELANE (0.54) | ELANEOPRK1KMT2AMEN1TDP1 | |
| SCHEMBL7960265 | 0.91 | ELANE (0.54) | ELANEOPRK1KMT2AMEN1TDP1 | |
| SCHEMBL7966257 | 0.90 | ELANE (0.53) | ELANEOPRK1TDP1HTR3APKM | |
| SCHEMBL7966256 | 0.90 | ELANE (0.53) | ELANEOPRK1TDP1HTR3APKM | |
| SCHEMBL7960167 | 0.90 | ELANE (0.53) | ELANEKDM4EOPRK1TDP1MAPK1 | |
| SCHEMBL7969507 | 0.88 | ELANE (0.52) | ELANEOPRK1TDP1MAPK1PKM | |
| SCHEMBL7957249 | 0.86 | ELANE (0.52) | ELANEHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331548-B1 | PREVENTION OR TREATMENT OF CYTOKINE RELATED DISEASES | SUNTORY LIMITED (JP) | 2001-12-18 | — | — | US | disclosed |