Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.57 |
| ▸ | P2RX1 | P51575 | 6/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.45 |
| ▸ | XPO1 | O14980 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811324 | 0.95 | TLR8 (0.64) | TLR8P2RX1P2RX7LMNAMEN1 | |
| SCHEMBL6816005 | 0.90 | TLR8 (0.55) | TLR8P2RX1P2RX7LMNAMEN1 | |
| SCHEMBL6816364 | 0.89 | TLR8 (0.54) | TLR8P2RX1P2RX7LMNAMEN1 | |
| SCHEMBL6815809 | 0.88 | P2RX1 (0.56) | TLR8P2RX1LMNAMEN1KMT2A | |
| SCHEMBL6819264 | 0.85 | TLR8 (0.53) | TLR8P2RX1P2RX7LMNAMEN1 | |
| SCHEMBL6814825 | 0.85 | MAPT (0.57) | TLR8P2RX1P2RX7LMNAMEN1 | |
| SCHEMBL6819508 | 0.85 | TLR8 (0.50) | TLR8P2RX1P2RX7LMNAMEN1 | |
| SCHEMBL6819166 | 0.84 | MAPT (0.56) | TLR8P2RX1P2RX7LMNAMEN1 | |
| SCHEMBL6819717 | 0.84 | KMT2A (0.56) | LMNAMEN1KMT2ATDP1NPC1 | |
| SCHEMBL6815832 | 0.83 | TLR8 (0.48) | TLR8P2RX1P2RX7LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262082-B1 | Diaminopyridine-containing thiourea inhibitors of herpes viruses | WYETH | 2001-07-17 | — | — | US | disclosed |