Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8347975 | 0.90 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6777867 | 0.89 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL6151288 | 0.89 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7948221 | 0.88 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL8684661 | 0.87 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL6767488 | 0.86 | EDNRA (0.80) | EDNRAEDNRB | |
| SCHEMBL4204130 | 0.85 | EDNRB (1.00) | EDNRAEDNRB | |
| SCHEMBL6640417 | 0.85 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6772268 | 0.85 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL6772703 | 0.85 | EDNRA (0.78) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760038-A | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-06-02 | — | — | US | claimed |
| EP-0725067-A1 | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-07 | — | — | EP | claimed |
| WO-2001049289-A1 | PHARMACEUTICAL AND VETERINARY USES OF ENDOTHELIN ANTAGONISTS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-07-12 | — | — | WO | disclosed |
| CN-1060172-C | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL MYERS SQUIBB CO (US) | 2001-01-03 | — | — | CN | disclosed |
| US-5780473-A | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-07-14 | — | — | US | disclosed |
| US-5760038-A | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| WO-1998004260-A1 | SUBSTITUTED BIPHENYL SULFONAMIDE ENDOTHELIN ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-02-05 | — | — | WO | disclosed |
| CN-1138581-A | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL MYERS SQUIBB CO (US) | 1996-12-25 | — | — | CN | disclosed |
| EP-0725067-A1 | Substituted biphenyl sulfonamide endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-07 | — | — | EP | disclosed |