SCHEMBL7947237

SCHEMBL7947237

O=Cc1ccc2cc(O)c(C=O)cc2c1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
PTGS2 P35354 1/20 0.50
RAB9A P51151 1/20 0.50
ERN1 O75460 4/20 0.42
ALDH5A1 P51649 3/20 0.42
ABAT P80404 3/20 0.42
ALDH1A1 P00352 3/20 0.42
TRIM24 O15164 2/20 0.42
TRIM33 Q9UPN9 2/20 0.42
TYR P14679 1/20 0.42
AOX1 Q06278 1/20 0.42
HPGD P15428 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP2A6 P11509 4/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10445586 0.88 KDM4E (0.64) KDM4EPTGS2RAB9AALDH5A1ABAT
SCHEMBL28970708 0.83 ERN1 (0.48) ERN1TRIM24TRIM33TYR
SCHEMBL6637472 0.82 TRIM24 (0.47) ERN1TRIM24TRIM33TYRTDP1
SCHEMBL6742400 0.82 TRIM24 (0.47) ERN1TRIM24TRIM33TYRTDP1
SCHEMBL10466277 0.80 TRIM24 (0.50) ERN1TRIM24TRIM33TYRTDP1
SCHEMBL31194371 0.79 TRIM24 (0.54) ERN1TRIM24TRIM33TYRTDP1
SCHEMBL669781 0.79 TRIM24 (0.54) ERN1TRIM24TRIM33TYRTDP1
SCHEMBL668600 0.79 TRIM24 (0.54) ERN1TRIM24TRIM33TYRTDP1
SCHEMBL4367977 0.79 KDM4E (0.48) KDM4EPTGS2RAB9AALDH5A1ABAT
SCHEMBL27908553 0.79 ERN1 (0.63) ERN1ALDH1A1TRIM24TRIM33TYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8853031-B2 Resist underlayer film composition and patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-10-07 US disclosed
US-20120184103-A1 RESIST UNDERLAYER FILM COMPOSITION AND PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-07-19 US disclosed
US-6252104-B1 3,6-DISUBSTITUTED-2-OXYNAPHTHALENE DERIVATIVES; RAW MATERIALS FOR SYNTHESIS OF SUCH MATERIALS AS DYES, PIGMENTS, PHOTOSENSITIVE MATERIALS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 2001-06-26 US disclosed
EP-0765858-B1 NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME UENO SEIYAKU OYO KENKYUJO KK (JP) 1999-12-22 EP disclosed
US-5847233-A Naphthol derivatives and process for producing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-12-08 US disclosed
US-5786523-A Naphthol derivatives and process for producing the same KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1998-07-28 US disclosed
EP-0765858-A1 NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1997-04-02 EP disclosed