Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.53 |
| ▸ | ATR | Q13535 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7948182 | 0.89 | MTOR (0.67) | MTOR | |
| SCHEMBL1832974 | 0.89 | MTOR (0.85) | MTORPIK3CA | |
| SCHEMBL7945749 | 0.82 | MTOR (0.64) | MTORPIK3CA | |
| SCHEMBL7944088 | 0.81 | MTOR (0.61) | MTOR | |
| SCHEMBL7945114 | 0.81 | MTOR (0.61) | MTOR | |
| SCHEMBL412976 | 0.80 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL1828434 | 0.80 | MTOR (0.82) | MTORPIK3CA | |
| SCHEMBL411975 | 0.80 | MTOR (0.89) | MTORPIK3CA | |
| SCHEMBL7943584 | 0.79 | MTOR (0.58) | MTOR | |
| SCHEMBL7936476 | 0.79 | MTOR (0.58) | MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010014939-A1 | PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2010-02-04 | — | — | WO | disclosed |