Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.63 |
| ▸ | MEN1 | O00255 | 11/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.63 |
| ▸ | LMNA | P02545 | 9/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PTGES | O14684 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2743113 | 0.92 | MAPT (0.66) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL19757536 | 0.84 | MAPT (0.68) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL1149228 | 0.82 | MAPT (0.73) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL7722872 | 0.80 | MAPT (0.75) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL6226561 | 0.80 | MAPT (0.74) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL12384468 | 0.79 | MAPT (0.64) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL330445 | 0.79 | MAPT (0.67) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL6231487 | 0.79 | MAPT (0.83) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL4728014 | 0.79 | MAPT (0.72) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL4725807 | 0.79 | MAPT (0.72) | MAPTMEN1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252104-B1 | 3,6-DISUBSTITUTED-2-OXYNAPHTHALENE DERIVATIVES; RAW MATERIALS FOR SYNTHESIS OF SUCH MATERIALS AS DYES, PIGMENTS, PHOTOSENSITIVE MATERIALS | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-0765858-B1 | NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | UENO SEIYAKU OYO KENKYUJO KK (JP) | 1999-12-22 | — | — | EP | disclosed |
| US-5847233-A | Naphthol derivatives and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-12-08 | — | — | US | disclosed |
| US-5786523-A | Naphthol derivatives and process for producing the same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0765858-A1 | NAPHTHOL DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1997-04-02 | — | — | EP | disclosed |