Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25620230 | 0.81 | TAAR1 (0.49) | IDO1HRH3TAAR1MAOBMAOA | |
| SCHEMBL7966000 | 0.79 | MAOB (0.46) | IDO1MAOBALDH1A1POLB | |
| SCHEMBL9278957 | 0.79 | MAOB (0.46) | IDO1MAOBALDH1A1POLB | |
| SCHEMBL7569694 | 0.78 | MAOB (0.38) | IDO1TAAR1MAOBALDH1A1POLB | |
| SCHEMBL28353912 | 0.78 | TAAR1 (0.50) | IDO1HRH3TAAR1MAOBACHE | |
| SCHEMBL7569529 | 0.77 | IDO1 (0.53) | IDO1TAAR1MAOBALDH1A1 | |
| SCHEMBL7868577 | 0.77 | GLA (0.43) | HRH3ALDH1A1 | |
| SCHEMBL1124900 | 0.77 | TAAR1 (0.52) | IDO1HRH3TAAR1MAOBMAOA | |
| SCHEMBL3102135 | 0.75 | TAAR1 (0.50) | IDO1HRH3TAAR1MAOBMAOA | |
| SCHEMBL3109159 | 0.75 | TAAR1 (0.50) | IDO1HRH3TAAR1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255349-B1 | PREVENTION REPRODUCTION; VIRICIDES | AMERICAN HOME PRODUCTS CORPORATION | 2001-07-03 | — | — | US | disclosed |