Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29853980 | 1.00 | NPC1 (0.31) | NPC1RAB9AKDM4EALDH1A1MAPK1 | |
| SCHEMBL29767683 | 0.78 | NPC1 (0.31) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28724487 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL28724488 | 0.76 | — | — | |
| SCHEMBL2814352 | 0.74 | — | — | |
| SCHEMBL28412797 | 0.73 | — | — | |
| SCHEMBL28855060 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL27185577 | 0.71 | NPC1 (0.32) | NPC1 | |
| Hydrochloric Acid SCHEMBL27185575 | 0.71 | — | — | |
| SCHEMBL28415281 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946575-B1 | FUSED RING SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW CHEMICAL CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-6034022-A | COORDINATION POLYMERIZATION CATALYST | THE DOW CHEMICAL COMPANY (US) | 2000-03-07 | — | — | US | disclosed |
| EP-0981556-A1 | ETHYLENE/ALPHA-OLEFIN/DIENE INTERPOLYMERS AND THEIR PREPARATION | THE DOW CHEMICAL COMPANY (US) | 2000-03-01 | — | — | EP | disclosed |
| US-5965756-A | COORDINATION CATALYSTS AS ADDITION POLYMERIZATION CATALYSTS | THE DOW CHEMICAL COMPANY (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0946575-A1 | FUSED RING SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998049212-A1 | ETHYLENE/ALPHA-OLEFIN/DIENE INTERPOLYMERS AND THEIR PREPARATION | THE DOW CHEMICAL COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| WO-1998027103-A1 | FUSED RING SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |