Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FKBP4 | Q02790 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28701342 | 1.00 | CA1 (0.43) | CA1CA9KMT2ACYP1A2CA2 | |
| SCHEMBL28581189 | 1.00 | CA1 (0.43) | CA1CA9KMT2ACYP1A2CA2 | |
| SCHEMBL28707537 | 1.00 | CA1 (0.43) | CA1CA9KMT2ACYP1A2CA2 | |
| SCHEMBL18268941 | 0.98 | CA1 (0.44) | CA1CA9KMT2ACYP1A2CA2 | |
| SCHEMBL18268907 | 0.98 | CA1 (0.44) | CA1CA9KMT2ACYP1A2CA2 | |
| SCHEMBL522959 | 0.91 | — | — | |
| SCHEMBL18268934 | 0.91 | — | — | |
| SCHEMBL4671527 | 0.88 | CA1 (0.50) | CA1CA9KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL29006364 | 0.87 | CA1 (0.50) | CA1CA9CYP1A2SMN1; SMN2 | |
| SCHEMBL11211397 | 0.86 | CA1 (0.48) | CA1CA9KMT2ACYP1A2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255276-B1 | MUSK MACROMOLECULE | GIVAUDEN ROURE (INTERNATIONAL) S.A. (CH) | 2001-07-03 | — | — | US | claimed |
| EP-0908455-A1 | Macrocycles | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1999-04-14 | — | — | EP | claimed |
| US-6255276-B1 | MUSK MACROMOLECULE | GIVAUDEN ROURE (INTERNATIONAL) S.A. (CH) | 2001-07-03 | — | — | US | disclosed |
| EP-0908455-A1 | Macrocycles | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1999-04-14 | — | — | EP | disclosed |