Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 16/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 14/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 12/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7943279 | 0.87 | HDAC3 (0.64) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL2405648 | 0.77 | MEN1 (0.52) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL22332695 | 0.75 | HDAC1 (0.89) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL2407868 | 0.71 | HDAC3 (0.71) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL2403209 | 0.71 | HDAC3 (0.71) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL2404865 | 0.70 | HDAC3 (0.68) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL2404858 | 0.70 | HDAC3 (0.68) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL2404272 | 0.69 | HDAC3 (0.64) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL2404278 | 0.69 | HDAC3 (0.64) | HDAC3HDAC1HDAC6HDAC2HDAC8 | |
| SCHEMBL2404193 | 0.69 | HDAC1 (0.78) | HDAC3HDAC1HDAC6HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010043953-A2 | NOVEL BRIDGED CYCLIC COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2010-04-22 | — | — | WO | disclosed |