SCHEMBL7947566

SCHEMBL7947566

CCCCSc1nsnc1[C@@H]1CN2CCC[C@@H]1C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 3/20 0.56
CHRM2 P08172 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4195842 1.00 CHRM1 (0.56) CHRM1CHRM2
SCHEMBL7810778 1.00 CHRM1 (0.56) CHRM1CHRM2
SCHEMBL7953015 1.00 CHRM1 (0.56) CHRM1CHRM2
SCHEMBL7810641 0.96 CHRM1 (0.55) CHRM1CHRM2
SCHEMBL7811583 0.95 CHRM2 (0.54) CHRM1CHRM2
SCHEMBL7810457 0.95 CHRM2 (0.54) CHRM1CHRM2
Oxalic Acid SCHEMBL7824503 0.94 CHRM1 (0.54) CHRM1CHRM2
SCHEMBL6459621 0.93 CHRM1 (0.64) CHRM1CHRM2
SCHEMBL5826272 0.93 CHRM1 (0.64) CHRM1CHRM2
SCHEMBL7949409 0.93 CHRM1 (0.64) CHRM1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271229-B1 ADMINISTERING A 1,2,5-OXADIAZOLE COMPOUND OR 1,2,5-THIADIAZOLE COMPOUND NOVO NORDISK A/S (DK) 2001-08-07 US claimed
WO-1996014316-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1996-05-17 WO claimed
US-6281232-B1 AZABICYCLIC RING-SUBSTITUTED THIA- OR OXADIAZOLES NOVO NORDISK A/S (DK) 2001-08-28 US disclosed
US-6281233-B1 AZABICYCLIC RING-SUBSTITUTED THIA- OR OXADIAZOLES NOVO NORDISK A/S (DK) 2001-08-28 US disclosed
US-6271229-B1 ADMINISTERING A 1,2,5-OXADIAZOLE COMPOUND OR 1,2,5-THIADIAZOLE COMPOUND NOVO NORDISK A/S (DK) 2001-08-07 US disclosed
US-6265419-B1 IRRITABLE BOWEL DISORDER NOVO NORDISK A/S (DK) 2001-07-24 US disclosed
EP-0709093-B1 Method for treating anxiety using an azabicyclic oxadiazole or thiadiazole compound LILLY CO ELI (US) 2000-04-05 EP disclosed
US-5612351-A AZABICYCLIC DERIVATIVES OF 1,2,3-OXA(OR THIA)DIAZOLE NOVO NORDISK A/S (DK) 1997-03-18 US disclosed
WO-1996014316-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1996-05-17 WO disclosed
WO-1996013166-A1 METHOD FOR TREATING ANXIETY ELI LILLY AND COMPANY (US) 1996-05-09 WO disclosed
EP-0709093-A2 Method for treating anxiety using an azabicyclic oxadiazole or thiadiazole compound ELI LILLY AND COMPANY (US) 1996-05-01 EP disclosed
US-5484794-A THIA- OR OXA-DIAZOLE COMPOUNDS ELI LILLY AND COMPANY (US) 1996-01-16 US disclosed