Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 12/20 | 0.81 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.81 |
| ▸ | GRIA4 | P48058 | 9/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2187213 | 1.00 | GRIA2 (0.81) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2188695 | 1.00 | GRIA2 (0.81) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2187209 | 1.00 | GRIA2 (0.81) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2188700 | 1.00 | GRIA2 (0.81) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2190042 | 0.91 | GRIA2 (0.81) | GRIA2KCNH2GRIA4 | |
| SCHEMBL2187140 | 0.91 | GRIA2 (0.81) | GRIA2KCNH2GRIA4 | |
| SCHEMBL3205517 | 0.91 | GRIA2 (0.81) | GRIA2KCNH2GRIA4 | |
| SCHEMBL4107314 | 0.90 | GRIA2 (1.00) | GRIA2KCNH2GRIA4 | |
| SCHEMBL4107318 | 0.90 | GRIA2 (1.00) | GRIA2KCNH2GRIA4 | |
| SCHEMBL4107311 | 0.90 | GRIA2 (1.00) | GRIA2KCNH2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038167-A1 | OXOPIPERIDINYL AND PYRANYL SULFONAMIDES AS AMPA POTENTIATORS | PFIZER INC. (US) | 2010-04-08 | — | — | WO | disclosed |