Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.61 |
| ▸ | CA2 | P00918 | 6/20 | 0.61 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11298047 | 1.00 | CA1 (0.61) | CA1CA2ZDHHC7ABCB1BIRC2 | |
| SCHEMBL2779851 | 1.00 | CA1 (0.61) | CA1CA2ZDHHC7ABCB1BIRC2 | |
| SCHEMBL28452311 | 0.98 | CA1 (0.59) | CA1CA2ZDHHC7ABCB1BIRC2 | |
| Iodide SCHEMBL2220838 | 0.98 | CA1 (0.59) | CA1CA2ZDHHC7ABCB1BIRC2 | |
| Ethane SCHEMBL28291164 | 0.98 | CA1 (0.59) | CA1CA2ZDHHC7ABCB1BIRC2 | |
| SCHEMBL6054956 | 0.98 | CA1 (0.59) | CA1CA2ZDHHC7ABCB1BIRC2 | |
| SCHEMBL5529335 | 0.93 | ZDHHC7 (0.60) | CA1CA2ZDHHC7ABCB1BIRC2 | |
| SCHEMBL3682137 | 0.93 | ZDHHC7 (0.60) | CA1CA2ZDHHC7ABCB1BIRC2 | |
| SCHEMBL16575041 | 0.93 | ZDHHC7 (0.60) | CA1CA2ZDHHC7ABCB1BIRC2 | |
| SCHEMBL560716 | 0.91 | ZDHHC7 (0.63) | CA1CA2ZDHHC7ABCB1BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130137667-A1 | LIGANDS FOR NEMATODE NUCLEAR RECEPTORS AND USES THEREOF | Board of Regents, Univesity of Texas System (US) | 2013-05-30 | — | — | US | disclosed |
| US-6265440-B1 | STOMACH ULCERS | R-TECH UENO, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-5886034-A | ANTIULCER AGENTS | KABUSHIKI KAISHA UENO SEIYAKU KENKYUJO (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5428062-A | Side effect reduction | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1995-06-27 | — | — | US | disclosed |
| US-5380709-A | Prostaglandins E and anti ulcers containing same | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5284858-A | Prostaglandins E and anti ulcers containing same | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1994-02-08 | — | — | US | disclosed |
| US-5225439-A | Side effect reduction | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1993-07-06 | — | — | US | disclosed |
| US-5166174-A | For duodenal ulcers or gastric ulcers | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0284180-B1 | PROSTAGLANDINS E AND ANTI ULCERS CONTAINING SAME | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1992-08-19 | — | — | EP | disclosed |
| EP-0284180-A1 | Prostaglandins E and anti ulcers containing same | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1988-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137667-A1 | LIGANDS FOR NEMATODE NUCLEAR RECEPTORS AND USES THEREOF | NR4A1, NR0B1, NR1H2 | CA1 4722/4885CA2 3508/4885ZDHHC7 2657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.