Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.58 |
| ▸ | FBP1 | P09467 | 4/20 | 0.47 |
| ▸ | PI4KA | P42356 | 2/20 | 0.43 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.43 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13977903 | 0.82 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BADORA3FBP1 | |
| SCHEMBL23885343 | 0.74 | ADORA2A (0.50) | ADORA2AADORA1ADORA2BADORA3FBP1 | |
| SCHEMBL30052744 | 0.74 | ADORA2A (0.50) | ADORA2AADORA1ADORA2BADORA3FBP1 | |
| SCHEMBL1755068 | 0.74 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3PI4KA | |
| SCHEMBL18526490 | 0.73 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BADORA3FBP1 | |
| SCHEMBL30052722 | 0.71 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL23885221 | 0.71 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL15689328 | 0.71 | ADORA2A (0.65) | ADORA2AADORA1ADORA2BADORA3FBP1 | |
| SCHEMBL29394367 | 0.71 | ADORA2A (0.65) | ADORA2AADORA1ADORA2BADORA3FBP1 | |
| SCHEMBL4055632 | 0.70 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172226-B1 | Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions | PERSEPTIVE BIOSYSTEMS, INC. | 2001-01-09 | — | — | US | disclosed |
| US-6133444-A | PURINE PEPTIDE NUCLEIC ACIDS SYNTHONS | PERSEPTIVE BIOSYSTEMS, INC. (US) | 2000-10-17 | — | — | US | disclosed |