Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 8/20 | 0.57 |
| ▸ | AKR1A1 | P14550 | 4/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.51 |
| ▸ | ILK | Q13418 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205581 | 0.88 | AKR1B1 (0.55) | AKR1B1AKR1A1PTGDR2ILK | |
| SCHEMBL7755700 | 0.86 | PTGDR2 (0.65) | AKR1B1AKR1A1PTGDR2ILK | |
| SCHEMBL7755971 | 0.79 | PTGDR2 (0.50) | AKR1B1AKR1A1PTGDR2ILK | |
| SCHEMBL7755682 | 0.75 | PTGDR2 (0.56) | AKR1B1AKR1A1PTGDR2 | |
| SCHEMBL444747 | 0.73 | AKR1B1 (1.00) | AKR1B1AKR1A1 | |
| SCHEMBL317185 | 0.70 | PTGDR2 (0.66) | AKR1B1PTGDR2 | |
| SCHEMBL7754412 | 0.69 | PTGDR2 (0.56) | AKR1B1AKR1A1PTGDR2 | |
| SCHEMBL21032143 | 0.69 | PTGDR2 (0.61) | AKR1B1PTGDR2 | |
| SCHEMBL21032474 | 0.69 | PTGDR2 (0.61) | AKR1B1AKR1A1PTGDR2 | |
| SCHEMBL2100600 | 0.67 | AKR1B1 (0.53) | AKR1B1AKR1A1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001064205-A2 | COMPOSITIONS CONTAINING A SUBSTITUTED INDOLEALKANOIC ACID AND AN ANGIOTENSIN CONVERTING ENZYME INHIBITOR | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2001-09-07 | — | — | WO | disclosed |