Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.57 |
| ▸ | PDE5A | O76074 | 3/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961851 | 1.00 | PDE4B (0.57) | PDE4BPDE5ANR3C1PDE4D | |
| SCHEMBL7947996 | 1.00 | PDE4B (0.57) | PDE4BPDE5ANR3C1PDE4D | |
| SCHEMBL7955305 | 0.91 | PDE4B (0.57) | PDE4BPDE5ANR3C1PDE4D | |
| SCHEMBL7955301 | 0.91 | PDE4B (0.57) | PDE4BPDE5ANR3C1PDE4D | |
| SCHEMBL4335267 | 0.88 | PDE4B (0.71) | PDE4BPDE5ANR3C1PDE4D | |
| SCHEMBL7957095 | 0.87 | PDE4B (0.53) | PDE4BPDE5ANR3C1PDE4D | |
| SCHEMBL7957085 | 0.87 | PDE4B (0.53) | PDE4BPDE5ANR3C1PDE4D | |
| SCHEMBL4339585 | 0.87 | PDE4B (0.72) | PDE4BPDE5ANR3C1PDE4D | |
| SCHEMBL7959140 | 0.87 | PDE4B (0.54) | PDE4BPDE5ANR3C1PDE4D | |
| SCHEMBL7959144 | 0.87 | PDE4B (0.54) | PDE4BPDE5ANR3C1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326379-B1 | ERECTILE DYSFUNCTION; CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. | 2001-12-04 | — | — | US | disclosed |