Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956024 | 0.88 | BACE1 (0.54) | BACE1CTSD | |
| SCHEMBL7948842 | 0.87 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL7947872 | 0.87 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL7957375 | 0.85 | BACE1 (0.56) | BACE1CTSD | |
| SCHEMBL7955228 | 0.84 | BACE1 (0.57) | BACE1CTSD | |
| SCHEMBL7955226 | 0.80 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL7950317 | 0.79 | BACE1 (0.49) | BACE1CTSD | |
| SCHEMBL7950496 | 0.78 | BACE1 (0.51) | BACE1CTSD | |
| SCHEMBL7969045 | 0.78 | BACE1 (0.48) | BACE1CTSD | |
| SCHEMBL7963570 | 0.77 | BACE1 (0.54) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021680-A2 | INHIBITORS OF BETA-SECRETASE | VITAE PHARMACEUTICALS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |