Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2634726 | 1.00 | GRM2 (0.70) | GRM2 | |
| SCHEMBL12030208 | 1.00 | GRM2 (0.70) | GRM2 | |
| SCHEMBL1039083 | 0.82 | GRM2 (1.00) | GRM2 | |
| SCHEMBL7955411 | 0.82 | GRM2 (0.71) | GRM2 | |
| SCHEMBL2634083 | 0.82 | GRM2 (0.71) | GRM2 | |
| SCHEMBL7950081 | 0.76 | GRM2 (0.46) | GRM2 | |
| SCHEMBL2634666 | 0.76 | GRM2 (0.46) | GRM2 | |
| SCHEMBL16944254 | 0.74 | GRM2 (1.00) | GRM2 | |
| SCHEMBL18334125 | 0.74 | GRM2 (0.76) | GRM2 | |
| SCHEMBL18334124 | 0.73 | GRM2 (1.00) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025890-A1 | 3-AZABICYCLO[3.1.0]HEXYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ORTHO-MCNEIL-JANSSEN PHARMACEUTICALS, INC (US) | 2010-03-11 | — | — | WO | disclosed |