SCHEMBL7948594

SCHEMBL7948594

CC(=O)NCC1[C@@H](O)[C@H](O)[C@@H](CO)N1C

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MGAM O43451 3/20 0.57
ENGASE Q8NFI3 2/20 0.55
GLA P06280 1/20 0.47
OGA O60502 4/20 0.38
FUCA1 P04066 1/20 0.38
GAA P10253 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL657350 1.00 MGAM (0.57) MGAMENGASEGLAOGAFUCA1
SCHEMBL14426737 1.00 MGAM (0.57) MGAMENGASEGLAOGAFUCA1
SCHEMBL14438740 1.00 MGAM (0.57) MGAMENGASEGLAOGAFUCA1
SCHEMBL15593247 0.82 MGAM (0.53) MGAMENGASEGAA
SCHEMBL7946703 0.81 ENGASE (0.48) MGAMENGASEGLAOGAFUCA1
SCHEMBL15593206 0.80 ENGASE (0.50) MGAMENGASEGLAOGAFUCA1
SCHEMBL19557623 0.80 ENGASE (0.50) MGAMENGASEGLAOGAFUCA1
SCHEMBL17124934 0.80 MGAM (0.50) MGAMENGASEGLAOGAFUCA1
SCHEMBL7945486 0.80 MGAM (0.50) MGAMENGASEGLAOGAFUCA1
SCHEMBL19557589 0.80 MGAM (0.50) MGAMENGASEGLAOGAFUCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010037207-A1 SELECTIVE GLYCOSIDASE INHIBITORS AND USES THEREOF SIMON FRASER UNIVERSITY (CA) 2010-04-08 WO disclosed