Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053202 | 0.89 | SRC (0.54) | SRCERN1TLR2TLR1TLR6 | |
| SCHEMBL20068035 | 0.86 | SRC (0.54) | SRCERN1TLR2TLR1TLR6 | |
| SCHEMBL11684737 | 0.80 | SRC (0.59) | SRCERN1TLR2TLR1TLR6 | |
| SCHEMBL1253814 | 0.79 | SRC (0.58) | SRCERN1TLR2TLR1TLR6 | |
| SCHEMBL15331107 | 0.79 | KMT2A (0.58) | SRCERN1TLR2TLR1TLR6 | |
| SCHEMBL2556723 | 0.78 | SRC (0.51) | SRCERN1TLR2TLR1TLR6 | |
| SCHEMBL15333363 | 0.78 | SRC (0.54) | SRCERN1TLR2TLR1TLR6 | |
| SCHEMBL6599199 | 0.77 | SRC (0.50) | SRCERN1TLR2TLR1TLR6 | |
| SCHEMBL2560107 | 0.77 | SRC (0.50) | SRCERN1TLR2TLR1TLR6 | |
| SCHEMBL3308881 | 0.77 | SRC (0.56) | SRCERN1TLR2TLR1TLR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |