⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7147398 | 0.77 | CA1 (0.37) | — | |
| SCHEMBL6575035 | 0.74 | — | — | |
| SCHEMBL11128375 | 0.74 | CA1 (0.36) | — | |
| SCHEMBL588402 | 0.72 | — | — | |
| SCHEMBL2456839 | 0.72 | — | — | |
| SCHEMBL7868272 | 0.72 | — | — | |
| Formaldehyde SCHEMBL8998516 | 0.72 | — | — | |
| SCHEMBL15068452 | 0.71 | CA1 (0.46) | — | |
| SCHEMBL634253 | 0.71 | — | — | |
| SCHEMBL15584 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262254-B1 | 8-FLUORO-9-((2-HYDROXYETHOXY)METHYL))GUANINE / (8-FLUOROACYCLOVIR) USEFUL AS ANTICANCER AND ANTIVIRAL AGENT | THE REGENTS OF UNIV. OF CALIFORNIA | 2001-07-17 | — | — | US | disclosed |
| US-5861503-A | FLUORINATING WITH FLUORINE OR ACETYL HYPOFLUORITE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-01-19 | — | — | US | disclosed |
| US-5628980-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1997-05-13 | — | — | US | disclosed |
| US-5614638-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1997-03-25 | — | — | US | disclosed |
| US-5591846-A | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. | 1997-01-07 | — | — | US | disclosed |
| EP-0431747-B1 | Stable liquid aqueous oxidant detergent | CLOROX CO (US) | 1996-11-20 | — | — | EP | disclosed |
| CN-1134700-A | Novel taxoids, their preparation and pharmaceutical compositions containing them | RHONE POULENC RORER SA (FR) | 1996-10-30 | — | — | CN | disclosed |
| EP-0728131-A1 | NOVEL TAXOIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 1996-08-28 | — | — | EP | disclosed |
| US-5464552-A | Surfactants with oxidation stable suspension using alkali metal chloride, borate or boric acid | THE CLOROX COMPANY (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0431838-B1 | Nonionic radiographic contrast agents | BRACCO INT BV (NL) | 1995-10-25 | — | — | EP | disclosed |
| WO-1995013271-A1 | NOVEL TAXOIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1995-05-18 | — | — | WO | disclosed |
| EP-0431838-A1 | Nonionic radiographic contrast agents | BRACCO INTERNATIONAL B.V. (NL) | 1991-06-12 | — | — | EP | disclosed |
| EP-0431747-A2 | Stable liquid aqueous oxidant detergent | The Clorox Company (US) | 1991-06-12 | — | — | EP | disclosed |
| US-5019289-A | Surfactants, metal peroxide | THE CLOROX COMPANY (US) | 1991-05-28 | — | — | US | disclosed |
| EP-0370596-A2 | Stable liquid detergent containing insoluble oxidant | The Clorox Company (US) | 1990-05-30 | — | — | EP | disclosed |
| US-4891147-A | PEROXIDE OF CALCIUM, MAGNESIUM OR ZINC | THE CLOROX COMPANY (US) | 1990-01-02 | — | — | US | disclosed |