Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 17/20 | 1.00 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.46 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.46 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7949008 | 1.00 | SRC (1.00) | SRCMCHR1TPSAB1TPSD1TPSG1 | |
| SCHEMBL7950233 | 0.88 | SRC (0.78) | SRC | |
| SCHEMBL7950229 | 0.88 | SRC (0.78) | SRC | |
| SCHEMBL8143905 | 0.85 | SRC (1.00) | SRCMCHR1 | |
| SCHEMBL8143902 | 0.85 | SRC (1.00) | SRCMCHR1 | |
| SCHEMBL7942708 | 0.82 | SRC (1.00) | SRC | |
| SCHEMBL7950799 | 0.81 | SRC (1.00) | SRCTPSAB1TPSD1TPSG1 | |
| SCHEMBL7950774 | 0.81 | SRC (1.00) | SRC | |
| SCHEMBL7952607 | 0.74 | SRC (0.85) | SRC | |
| SCHEMBL8142579 | 0.74 | SRC (0.79) | SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068655-A2 | CAPROLACTAM DERIVATIVES AND USES THEREOF | ARIAD PHARMACEUTICALS, INC. (US) | 2001-09-20 | — | — | WO | claimed |