Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 19/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775889 | 0.90 | ANO1 (0.58) | ANO1MEN1MAPTKMT2AANO2 | |
| SCHEMBL1954491 | 0.82 | KMT2A (0.54) | ANO1MEN1MAPTKMT2A | |
| SCHEMBL1795098 | 0.77 | ANO1 (0.64) | ANO1ANO2 | |
| SCHEMBL1954102 | 0.77 | ANO1 (0.61) | ANO1MEN1KMT2AANO2 | |
| SCHEMBL1954403 | 0.77 | ANO1 (0.60) | ANO1ANO2 | |
| SCHEMBL28599811 | 0.77 | MEN1 (0.79) | ANO1MEN1MAPTKMT2AANO2 | |
| SCHEMBL1954278 | 0.75 | ANO1 (0.65) | ANO1MEN1KMT2AANO2 | |
| SCHEMBL1954847 | 0.75 | ANO1 (0.68) | ANO1MEN1KMT2AANO2 | |
| SCHEMBL1953118 | 0.75 | ANO1 (0.58) | ANO1MEN1KMT2AANO2 | |
| SCHEMBL1952182 | 0.75 | KDM4E (0.57) | ANO1MEN1MAPTKMT2AANO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |