Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.51 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6121028 | 1.00 | HTR2C (0.63) | HTR2CSMN1; SMN2NPC1RAB9ACACNA1G | |
| SCHEMBL7646354 | 1.00 | HTR2C (0.63) | HTR2CSMN1; SMN2NPC1RAB9ACACNA1G | |
| SCHEMBL6121024 | 1.00 | HTR2C (0.63) | HTR2CSMN1; SMN2NPC1RAB9ACACNA1G | |
| SCHEMBL1509015 | 1.00 | HTR2C (0.63) | HTR2CSMN1; SMN2NPC1RAB9ACACNA1G | |
| SCHEMBL3652770 | 0.90 | HTR2C (0.76) | HTR2CSMN1; SMN2NPC1RAB9ACACNA1G | |
| SCHEMBL16467962 | 0.90 | HTR2C (0.76) | HTR2CSMN1; SMN2NPC1RAB9ACACNA1G | |
| SCHEMBL15924239 | 0.87 | HTR2C (0.57) | HTR2CSMN1; SMN2NPC1RAB9ACACNA1G | |
| SCHEMBL13567884 | 0.85 | HTR2C (0.55) | HTR2CSMN1; SMN2NPC1RAB9ACACNA1G | |
| SCHEMBL3941416 | 0.84 | SMN1; SMN2 (0.57) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL4431805 | 0.84 | HTR2C (0.72) | HTR2CSMN1; SMN2NPC1RAB9ACACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009151069-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIRO[2.5]OCTANE RING STRUCTURE | 第一三共株式会社 (JP) | 2009-12-17 | — | — | WO | disclosed |