SCHEMBL7950722

SCHEMBL7950722

C=C(C=O)CC1=CCC2CC1C2(C)C

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.51
KDM4E B2RXH2 1/20 0.51
HTT P42858 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
MAPK1 P28482 3/20 0.46
CXCR3 P49682 14/20 0.44
KCNH2 Q12809 1/20 0.41
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4620514 0.84 TSHR (0.49) TSHRKDM4EHTTTDP1MAPK1
SCHEMBL17204582 0.79 TSHR (0.48) TSHRKDM4EHTTTDP1MAPK1
SCHEMBL3505958 0.76 MAPK1 (0.51) TSHRKDM4EHTTTDP1MAPK1
SCHEMBL14484582 0.76 MAPK1 (0.51) TSHRKDM4EHTTTDP1MAPK1
SCHEMBL9000551 0.75 TSHR (0.52) TSHRKDM4EHTTTDP1MAPK1
Myrtenol SCHEMBL24281940 0.74 TSHR (0.58) TSHRKDM4EHTTTDP1MAPK1
Myrtenol SCHEMBL155709 0.74 TSHR (0.58) TSHRKDM4EHTTTDP1MAPK1
Myrtenol SCHEMBL4826734 0.74 TSHR (0.58) TSHRKDM4EHTTTDP1MAPK1
Myrtenol SCHEMBL3836506 0.74 TSHR (0.58) TSHRKDM4EHTTTDP1MAPK1
Myrtenol SCHEMBL15536292 0.74 TSHR (0.58) TSHRKDM4EHTTTDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001085663-A1 BICYCLOHEPTENYL COMPOUNDS COGNIS DEUTSCHLAND GMBH & CO. KG (DE) 2001-11-15 WO disclosed