Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | PRNP | P04156 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1907496 | 0.92 | ANO1 (0.83) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1953247 | 0.82 | ANO1 (1.00) | ANO1 | |
| SCHEMBL1907632 | 0.82 | ANO1 (0.79) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL13926384 | 0.81 | MEN1 (0.84) | MEN1KMT2ANPC1RAB9AGRIN2C | |
| SCHEMBL13926183 | 0.80 | MEN1 (0.56) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1907612 | 0.80 | ANO1 (0.76) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1954104 | 0.80 | ANO1 (0.74) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12271351 | 0.79 | ANO1 (0.64) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL21259152 | 0.75 | MEN1 (0.80) | ANO1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1951568 | 0.75 | MEN1 (0.71) | ANO1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027875-A2 | COMPOUNDS THAT MODULATE INTRACELLULAR CALCIUM | CALCIMEDICA INC. (US) | 2010-03-11 | — | — | WO | disclosed |