Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879447 | 0.83 | BCHE (0.47) | MAPTTDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL14622099 | 0.80 | KDM4E (0.44) | MAPTSMN1; SMN2KDM4EALDH1A1MEN1 | |
| SCHEMBL7805020 | 0.79 | PTGER4 (0.53) | MAPTTDP1L3MBTL1PTGER4PTGER3 | |
| SCHEMBL17694446 | 0.79 | MEN1 (0.50) | MAOBMAPTTDP1L3MBTL1CYP2C9 | |
| SCHEMBL8980650 | 0.79 | MAOB (0.54) | MAOBMAPTTDP1L3MBTL1CYP2C9 | |
| SCHEMBL8489879 | 0.77 | MAPT (0.57) | MAOBMAPTTDP1L3MBTL1CYP2C9 | |
| SCHEMBL4226079 | 0.77 | BCHE (0.43) | MAPTTDP1L3MBTL1CYP2C9CYP2C19 | |
| SCHEMBL4234474 | 0.77 | BCHE (0.65) | L3MBTL1KDM4EBCHE | |
| SCHEMBL3251271 | 0.76 | CYP3A4 (0.47) | MAPTCYP2C19SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL4963194 | 0.76 | BCHE (0.43) | MAOBMAPTTDP1L3MBTL1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218427-B1 | AS ENDOTHELIN RECEPTOR ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-0924207-A1 | CHROMENE-3-CARBOXYLATE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |