Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 17/20 | 0.52 |
| ▸ | NMBR | P28336 | 1/20 | 0.49 |
| ▸ | GRPR | P30550 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253241 | 1.00 | TACR1 (0.52) | TACR1NMBRGRPRMEN1KMT2A | |
| SCHEMBL7177193 | 0.95 | TACR1 (0.48) | TACR1NMBRGRPR | |
| SCHEMBL6250373 | 0.93 | TACR1 (0.53) | TACR1NMBRGRPR | |
| SCHEMBL6255756 | 0.90 | TACR1 (0.65) | TACR1 | |
| SCHEMBL6254154 | 0.89 | TACR1 (0.53) | TACR1 | |
| SCHEMBL6251629 | 0.89 | TACR1 (0.55) | TACR1 | |
| SCHEMBL6253439 | 0.89 | TACR1 (0.53) | TACR1 | |
| SCHEMBL6251983 | 0.88 | TACR1 (0.53) | TACR1 | |
| SCHEMBL6254232 | 0.88 | TACR1 (0.66) | TACR1 | |
| SCHEMBL6250596 | 0.88 | TACR1 (0.65) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194437-B1 | ANTIDEPRESSANTS; ANTICANCER AGENTS; GASTROINTESTINAL DISORDERS; COGNITION ACTIVATORS | WARNER-LAMBERT COMPANY | 2001-02-27 | — | — | US | disclosed |