Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28366599 | 0.89 | NPC1 (0.38) | S1PR1NPC1HPGDRAB9ASKP2 | |
| SCHEMBL28875936 | 0.89 | NPC1 (0.38) | S1PR1NPC1HPGDRAB9ASKP2 | |
| SCHEMBL9356293 | 0.86 | S1PR1 (0.42) | S1PR1PPARGPPARA | |
| SCHEMBL29813604 | 0.85 | SKP2 (0.39) | S1PR1NPC1HPGDRAB9ASKP2 | |
| SCHEMBL7949604 | 0.85 | HSPA5 (0.38) | — | |
| SCHEMBL28058768 | 0.81 | HTT (0.43) | NPC1HPGDRAB9ASKP2MAPK1 | |
| SCHEMBL9862552 | 0.80 | PPARG (0.42) | S1PR1PPARGPPARA | |
| SCHEMBL18951294 | 0.77 | APEX1 (0.34) | S1PR1SKP2 | |
| SCHEMBL7950342 | 0.77 | HTT (0.48) | NPC1MAPK1HTTNPSR1PPARG | |
| SCHEMBL7949239 | 0.76 | HTT (0.47) | NPC1MAPK1HTTNPSR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6231804-B1 | USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER | CHISSO CORPORATION (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-0972800-A1 | MODIFIED OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PREPARING THE SAME, AND MODIFIED OLEFIN (CO)POLYMER COMPOSITION MOLDING | CHISSO CORPORATION (JP) | 2000-01-19 | — | — | EP | disclosed |