Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL6542238 | 0.76 | — | — | |
| SCHEMBL31586817 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ACXCR4CHRM5 | |
| SCHEMBL9801548 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ACXCR4CHRM5 | |
| SCHEMBL22320733 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ACXCR4CHRM5 | |
| SCHEMBL28343762 | 0.72 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ACXCR4CHRM5 | |
| SCHEMBL104625 | 0.72 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2ACXCR4CHRM5 | |
| SCHEMBL25455016 | 0.71 | TOP2A (0.41) | SMN1; SMN2POLB | |
| SCHEMBL3094801 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2ACXCR4CHRM5 | |
| SCHEMBL24462563 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2ACHRM5CHRM3 | |
| Hydrochloric Acid SCHEMBL25326103 | 0.70 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2ACXCR4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6264966-B1 | DEODORANTS; THERAPY FOR ORAL DISEASES | CONCAT, LTD. | 2001-07-24 | — | — | US | disclosed |