SCHEMBL7951376

SCHEMBL7951376

Fc1c(F)c(Cl)c(Cl)c(C(F)(F)F)c1F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7959691 0.94 NOTUM (0.33) NOTUM
SCHEMBL8459110 0.92 NOTUM (0.34) NOTUM
SCHEMBL11267899 0.86 NOTUM (0.34) NOTUM
SCHEMBL7069317 0.83 TSHR (0.33) NOTUM
SCHEMBL11261942 0.82 NOTUM (0.36) NOTUM
SCHEMBL28517192 0.82 NOTUM (0.36) NOTUM
SCHEMBL28124076 0.78
SCHEMBL11264290 0.78 NOTUM (0.33) NOTUM
SCHEMBL10357220 0.77 TSHR (0.31) NOTUM
SCHEMBL11602548 0.75 NOTUM (0.42) NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118119583-A Method for producing fluorine-containing aromatic compound 大金工业株式会社 2024-05-31 CN disclosed
US-6265627-B1 HEATING HALOGEN-CONTAINING AROMATIC COMPOUNDS WITH AN ALKALI METAL FLUORIDE IN PRESENCE OF N,N'N?-HEXA-SUBSTITUTED GUANIDINIUM HALIDE AS CATALYST TO PRODUCE POLYFLUOROAROMATIC COMPOUND Igumnov, Sergei Mikhailovich (RU) 2001-07-24 US disclosed
EP-0023647-B1 Process for the preparation of halogenated benzoyl fluorides BAYER AG (DE) 1982-06-30 EP disclosed
US-4330366-A Process for the preparation of halogenated benzoyl fluorides BAYER AKTIENGESELLSCHAFT (DE) 1982-05-18 US disclosed
EP-0023647-A1 Process for the preparation of halogenated benzoyl fluorides BAYER AG (DE) 1981-02-11 EP disclosed