Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 18/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | CASR | P41180 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951533 | 1.00 | ADRB3 (0.64) | ADRB3ADRB1ADRB2CYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL7963704 | 0.99 | ADRB3 (0.63) | ADRB3ADRB1ADRB2CYP2D6SLC6A2 | |
| Hydrochloric Acid SCHEMBL7963699 | 0.99 | ADRB3 (0.63) | ADRB3ADRB1ADRB2CYP2D6SLC6A2 | |
| SCHEMBL7970016 | 0.91 | ADRB3 (0.77) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7970013 | 0.91 | ADRB3 (0.77) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL7959883 | 0.91 | ADRB3 (0.77) | ADRB3ADRB1ADRB2 | |
| Hydrochloric Acid SCHEMBL7959888 | 0.91 | ADRB3 (0.77) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6393880 | 0.86 | ADRB3 (0.55) | ADRB3ADRB1ADRB2CYP2D6SLC6A2 | |
| SCHEMBL6393871 | 0.86 | ADRB3 (0.55) | ADRB3ADRB1ADRB2CYP2D6SLC6A2 | |
| SCHEMBL7976392 | 0.86 | ADRB3 (0.67) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265581-B1 | REACTING SPECIFIED EPOXIDE AND AMINE, REACTING PRODUCT WITH ACID TO FORM ACID ADDITION SALT | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6075040-A | OBESITY AND DIABETES | ELI LILLY AND COMPANY (US) | 2000-06-13 | — | — | US | disclosed |
| US-6060492-A | SIDE EFFECT REDUCTION | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| US-5977154-A | OBESITY, DIABETES | ELI LILLY AND COMPANY (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0764640-A1 | Selective beta3 adrenergic agonists | ELI LILLY AND COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |