SCHEMBL7951946

SCHEMBL7951946

O=C(O)C1CC(=O)N(CCN2C[C@H](C(=O)O)CC2=O)C1

nearest known ligand 0.66

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.66
SMN1; SMN2 Q16637 2/20 0.62
HTT P42858 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.54
MAPT P10636 1/20 0.53
ALDH1A1 P00352 1/20 0.51
HPGD P15428 2/20 0.49
GAA P10253 1/20 0.49
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
RECQL P46063 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1538426 1.00 POLB (0.66) POLBSMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL10922468 0.90 POLB (0.60) POLBSMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL31537583 0.90 POLB (0.60) POLBSMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL15082395 0.90 POLB (0.60) POLBSMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL31537602 0.90 POLB (0.60) POLBSMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL316989 0.89 POLB (0.63) POLBSMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL338776 0.89 POLB (0.58) POLBSMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL15082385 0.89 POLB (0.58) POLBSMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL5843184 0.88 POLB (0.54) POLBSMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL5499784 0.88 POLB (0.66) POLBSMN1; SMN2HTTL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001059161-A2 ANALYTE ASSAYS EMPLOYING UNIVERSAL ARRAYS CLONTECH LABORATORIES, INC. (US) 2001-08-16 WO disclosed