Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7957198 | 0.86 | EDNRB (0.75) | EDNRBEDNRA | |
| SCHEMBL7954029 | 0.83 | EDNRB (0.56) | EDNRBEDNRA | |
| SCHEMBL7944100 | 0.81 | EDNRB (0.65) | EDNRBEDNRA | |
| SCHEMBL7950870 | 0.81 | EDNRB (0.84) | EDNRBEDNRA | |
| SCHEMBL7943804 | 0.76 | EDNRB (0.87) | EDNRBEDNRA | |
| SCHEMBL7956806 | 0.71 | EDNRB (0.64) | EDNRBEDNRA | |
| SCHEMBL7943809 | 0.71 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL7954672 | 0.69 | — | — | |
| SCHEMBL7950518 | 0.69 | EDNRB (0.63) | EDNRB | |
| SCHEMBL10383691 | 0.68 | MAPT (0.55) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218427-B1 | AS ENDOTHELIN RECEPTOR ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |