Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.43 |
| ▸ | MAOB | P27338 | 11/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7952163 | 0.85 | NPC1 (0.50) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL561194 | 0.84 | NPC1 (0.56) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL7942151 | 0.83 | CYP3A4 (0.53) | NPC1RAB9AMAPTHRH3ALDH1A1 | |
| SCHEMBL9514414 | 0.81 | MAPT (0.48) | NPC1RAB9AMAPTMAOBPOLB | |
| SCHEMBL3688238 | 0.81 | NPC1 (0.53) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL29895646 | 0.81 | NPC1 (0.53) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL7952166 | 0.79 | NPC1 (0.47) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL128091 | 0.77 | NPC1 (0.81) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL8764585 | 0.77 | NPC1 (0.62) | NPC1RAB9AMAPTHRH3MAOB | |
| SCHEMBL17552972 | 0.77 | NPC1 (0.49) | NPC1RAB9AMAPTHRH3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6231804-B1 | USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER | CHISSO CORPORATION (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-0972800-A1 | MODIFIED OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PREPARING THE SAME, AND MODIFIED OLEFIN (CO)POLYMER COMPOSITION MOLDING | CHISSO CORPORATION (JP) | 2000-01-19 | — | — | EP | disclosed |