Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SELP | P16109 | 3/20 | 0.38 |
| ▸ | SELL | P14151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1492751 | 0.82 | AKR1C1 (0.51) | AKR1C1MEN1KMT2ATSHRHDAC4 | |
| SCHEMBL31292176 | 0.80 | AKR1C1 (0.49) | AKR1C1MEN1KMT2ATSHRMAP4K4 | |
| SCHEMBL29514621 | 0.79 | AKR1C1 (0.66) | AKR1C1MEN1KMT2ATSHRHDAC4 | |
| SCHEMBL1670449 | 0.79 | AKR1C1 (0.47) | AKR1C1MEN1KMT2ATSHRHDAC4 | |
| SCHEMBL4827944 | 0.77 | AKR1C1 (0.68) | AKR1C1MEN1KMT2ATSHRHDAC4 | |
| SCHEMBL1669766 | 0.75 | AKR1C1 (0.42) | AKR1C1ALDH1A1 | |
| SCHEMBL9280861 | 0.75 | AKR1C3 (0.43) | AKR1C1MEN1KMT2ATSHR | |
| SCHEMBL23163719 | 0.74 | MEN1 (0.42) | AKR1C1MEN1KMT2ATSHRSELP | |
| SCHEMBL66387 | 0.72 | AKR1C1 (0.96) | AKR1C1MEN1KMT2ATSHRHDAC4 | |
| SCHEMBL19249602 | 0.72 | AKR1C1 (0.96) | AKR1C1MEN1KMT2ATSHRHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187928-B1 | TREATING FUNGAL DISEASES | THE ROCKEFELLER UNIVERSITY | 2001-02-13 | — | — | US | disclosed |
| US-6087510-A | Method of use of imidazolium cations | THE ROCKEFELLER UNIVERSITY (US) | 2000-07-11 | — | — | US | disclosed |
| US-5969150-A | FLUORESCENT COMPOUNDS FOR MEDICAL DIAGNOSIS, DRUGS AND LABELS OR FUNGICIDES AND VIRICIDES | THE ROCKEFELLER UNIVERSITY (US) | 1999-10-19 | — | — | US | disclosed |
| US-5874587-A | FLUORESCENCE | THE ROCKEFELLER UNIVERSITY (US) | 1999-02-23 | — | — | US | disclosed |