Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7954376 | 0.99 | KMT2A (0.56) | KMT2ASMN1; SMN2THRBALDH1A1L3MBTL1 | |
| SCHEMBL7955059 | 0.94 | KMT2A (0.57) | KMT2ASMN1; SMN2THRBALDH1A1L3MBTL1 | |
| SCHEMBL4588624 | 0.88 | KMT2A (0.59) | KMT2ASMN1; SMN2THRBALDH1A1L3MBTL1 | |
| SCHEMBL6270349 | 0.86 | KMT2A (0.54) | KMT2ASMN1; SMN2THRBALDH1A1L3MBTL1 | |
| SCHEMBL7945846 | 0.84 | NPC1 (0.64) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL13973367 | 0.84 | KMT2A (0.58) | KMT2ASMN1; SMN2THRBALDH1A1L3MBTL1 | |
| SCHEMBL7945968 | 0.83 | NPC1 (0.66) | KMT2ASMN1; SMN2ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL9128679 | 0.82 | KMT2A (0.57) | KMT2ASMN1; SMN2THRBALDH1A1L3MBTL1 | |
| SCHEMBL5841851 | 0.82 | KMT2A (0.57) | KMT2ASMN1; SMN2THRBALDH1A1L3MBTL1 | |
| SCHEMBL7372978 | 0.82 | HDAC3 (0.57) | KMT2ASMN1; SMN2THRBALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |