⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334940 | 0.64 | — | — | |
| SCHEMBL23817294 | 0.62 | PDE10A (0.42) | — | |
| SCHEMBL23143459 | 0.61 | KDR (0.54) | — | |
| SCHEMBL18952898 | 0.57 | — | — | |
| SCHEMBL958858 | 0.54 | — | — | |
| SCHEMBL4067471 | 0.53 | — | — | |
| SCHEMBL11296536 | 0.51 | — | — | |
| SCHEMBL2532418 | 0.51 | CYP19A1 (0.32) | — | |
| SCHEMBL373166 | 0.48 | HSP90AA1 (0.50) | — | |
| SCHEMBL21578108 | 0.47 | HSP90AA1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745154-B1 | MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES AND METHOD OF USING THIS SYSTEM | LIGNOZYM GMBH (DE) | 1998-09-16 | — | — | EP | claimed |
| WO-1997034891-A1 | SUBSTITUTED 1,3-THIAZOLIDINES AND 1,3-THIAZOLIDIN-4-ONES, METHOD FOR PREPARING SAME, AND USE THEREOF AS DRUGS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-09-25 | — | — | WO | claimed |
| JP-1228991-A | — | — | None | — | — | JP | disclosed |
| CN-122010947-A | Antagonists of adenosine A2a receptors | 阿道尔克斯治疗有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-118853594-A | Chimeric poxvirus compositions and uses thereof | 希望之城 | 2024-10-29 | — | — | CN | disclosed |
| CN-118834840-A | Chimeric poxvirus compositions and uses thereof | 希望之城 | 2024-10-25 | — | — | CN | disclosed |
| US-20240217978-A1 | COMPOUND AS ADENOSINE A2a RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2024-07-04 | — | — | US | disclosed |
| US-12012467-B2 | Small molecule DCN1 inhibitors and therapeutic methods using the same | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-18 | — | — | US | disclosed |
| CN-117701562-A | RNAi agents and compositions for inhibiting expression of angiopoietin-like 3 (ANGPTL 3) and methods of use | 箭头药业股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-4326724-A1 | COMPOUND AS ADENOSINE A2A RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2024-02-28 | — | — | EP | disclosed |
| CN-111343994-B | RNAi agents and compositions for inhibiting expression of angiopoietin-like 3 (ANGPTL 3) and methods of use | 箭头药业股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| JP-H01228991-A | SUBSTITUTED 1,2,4-TRIAZOLO(1,5-A)TRIAZINE AS BRONCHODILATOR | RIKER LAB INC | 1989-09-12 | — | — | JP | disclosed |
| EP-0281367-A1 | Substituted 1,2,4-triazolo[1,5-a]triazines as bronchodilators | RIKER LABORATORIES, INC. (US) | 1988-09-07 | — | — | EP | disclosed |
| EP-0281367-A1 | Substituted 1,2,4-triazolo[1,5-a]triazines as bronchodilators | RIKER LABORATORIES, INC. (US) | 1988-09-07 | — | — | EP | disclosed |
| EP-0281367-A1 | Substituted 1,2,4-triazolo[1,5-a]triazines as bronchodilators | RIKER LABORATORIES, INC. (US) | 1988-09-07 | — | — | EP | disclosed |
| US-4734413-A | Substituted 1,2,4-triazolo[1,5-A]triazines as bronchodilators | RIKER LABORATORIES, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4734413-A | Substituted 1,2,4-triazolo[1,5-A]triazines as bronchodilators | RIKER LABORATORIES, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4734413-A | Substituted 1,2,4-triazolo[1,5-A]triazines as bronchodilators | RIKER LABORATORIES, INC. (US) | 1988-03-29 | — | — | US | disclosed |
| US-4617304-A | VIRICIDE; HERPES | MERCK & CO., INC. (US) | 1986-10-14 | — | — | US | disclosed |
| EP-0159264-A2 | Antiviral compounds | MERCK & CO. INC. (US) | 1985-10-23 | — | — | EP | disclosed |