SCHEMBL7954045

SCHEMBL7954045

CCCCCCCCCc1cc(C)ccc1OP(O)F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.39
GAA P10253 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
THRB P10828 2/20 0.39
ALDH1A1 P00352 1/20 0.39
ALOX5 P09917 6/20 0.39
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 2/20 0.39
HTT P42858 2/20 0.39
KMT2A Q03164 2/20 0.39
TYR P14679 2/20 0.39
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PTGS2 P35354 4/20 0.38
MAPK1 P28482 1/20 0.38
RAD52 P43351 1/20 0.38
THRA P10827 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7954042 0.88 MAPT (0.41) MAPTGAANPSR1THRBALDH1A1
SCHEMBL11619606 0.88 MAPT (0.41) MAPTGAANPSR1THRBALDH1A1
SCHEMBL7954047 0.86 MAPT (0.38) MAPTGAANPSR1THRBALDH1A1
SCHEMBL7949239 0.86 HTT (0.47) MAPTNPSR1THRBALDH1A1TDP1
SCHEMBL7950342 0.84 HTT (0.48) MAPTNPSR1THRBALDH1A1TDP1
SCHEMBL10469151 0.82 MAPT (0.40) MAPTGAANPSR1THRBALDH1A1
SCHEMBL11487795 0.80 MAPT (0.46) MAPTGAANPSR1THRBALDH1A1
SCHEMBL11482268 0.80 MAPT (0.46) MAPTGAANPSR1THRBALDH1A1
SCHEMBL28058768 0.79 HTT (0.43) MAPTNPSR1THRBALDH1A1TDP1
SCHEMBL15186292 0.79 HTR2A (0.53) GAAALOX5TDP1L3MBTL1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6231804-B1 USED FOR HOLLOW CONTAINERS, A FILM, A SHEET, A PIPE, FIBER AND MOLDING;A BLEND OF HIGH MOLECULAR WEIGHT POLYETHYLENE COPOLYMER,AN OLEFIN HOMO OR COPLYMER CHISSO CORPORATION (JP) 2001-05-15 US disclosed
EP-0972800-A1 MODIFIED OLEFIN (CO)POLYMER COMPOSITION, PROCESS FOR PREPARING THE SAME, AND MODIFIED OLEFIN (CO)POLYMER COMPOSITION MOLDING CHISSO CORPORATION (JP) 2000-01-19 EP disclosed