Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8417579 | 0.97 | — | — | |
| SCHEMBL7960892 | 0.83 | — | — | |
| SCHEMBL7956081 | 0.81 | — | — | |
| SCHEMBL7954087 | 0.80 | MCL1 (0.31) | MCL1 | |
| SCHEMBL8416084 | 0.79 | — | — | |
| SCHEMBL8417576 | 0.78 | POLB (0.31) | — | |
| SCHEMBL7960925 | 0.76 | HPGD (0.42) | MCL1 | |
| SCHEMBL7952021 | 0.76 | MCL1 (0.47) | MCL1 | |
| SCHEMBL7966685 | 0.75 | BRD4 (0.31) | — | |
| SCHEMBL7947061 | 0.74 | SRD5A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271251-B1 | CARDIOVASCULAR DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY LIMITED (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-0787728-A1 | Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-08-06 | — | — | EP | disclosed |