Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 11/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27474223 | 0.97 | CNR1 (0.47) | CNR1CREBBPBAZ2BBAZ2ATNF | |
| SCHEMBL7954482 | 0.87 | CNR1 (0.46) | CNR1CREBBPBAZ2BBAZ2ATNF | |
| SCHEMBL7947040 | 0.83 | CNR1 (0.46) | CNR1CREBBPTDP1L3MBTL1 | |
| SCHEMBL27474224 | 0.80 | CNR1 (0.45) | CNR1CREBBPTNFTDP1L3MBTL1 | |
| SCHEMBL7955770 | 0.79 | CNR1 (0.41) | CNR1BAZ2BBAZ2APOLB | |
| SCHEMBL7954138 | 0.75 | TNF (0.40) | TNFTDP1L3MBTL1 | |
| SCHEMBL8960027 | 0.68 | CNR1 (0.66) | CNR1CREBBPTNFLMNAPOLB | |
| SCHEMBL13131391 | 0.68 | CNR1 (0.46) | CNR1CREBBPTNF | |
| SCHEMBL8408536 | 0.67 | TNF (0.45) | TNFTDP1L3MBTL1 | |
| SCHEMBL23852674 | 0.66 | TNF (0.50) | CNR1TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271251-B1 | CARDIOVASCULAR DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY LIMITED (JP) | 2001-08-07 | — | — | US | disclosed |
| CN-1058969-C | Novel substd. guanidine derivs., process for prodn. thereof, and pharmaceutical uses thereof | SUMITOMO PHARMA (JP) | 2000-11-29 | — | — | CN | disclosed |
| US-5977100-A | Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5834454-A | TREATMENT OF ANGINA, ISCHEMIA, ARRHYTHMIA | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0787728-A1 | Substituted guanidine derivatives, process for production thereof, and pharmaceutical uses thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-08-06 | — | — | EP | disclosed |