Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468995 | 0.93 | HRH1 (0.49) | HRH1 | |
| SCHEMBL7464691 | 0.91 | TACR2 (0.55) | TACR2HRH1 | |
| SCHEMBL7464461 | 0.90 | HRH1 (0.63) | TACR2HRH1 | |
| SCHEMBL7471722 | 0.90 | HRH1 (0.62) | TACR2HRH1 | |
| SCHEMBL7473923 | 0.88 | HRH1 (0.58) | TACR2HRH1 | |
| SCHEMBL7477013 | 0.87 | HRH1 (0.63) | TACR2HRH1 | |
| SCHEMBL7472802 | 0.87 | HRH1 (0.59) | TACR2HRH1 | |
| SCHEMBL7470053 | 0.86 | HRH1 (0.52) | TACR2HRH1 | |
| SCHEMBL7472958 | 0.86 | TACR2 (0.50) | TACR2HRH1 | |
| SCHEMBL7470451 | 0.86 | HRH1 (0.56) | TACR2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297259-B1 | HISTAMINE RECEPTOR ANTAGONISTS AND TACHYKININ RECEPTOR ANTAGONISTS. | AVENTIS PHARMACEUTICALS INC. | 2001-10-02 | — | — | US | disclosed |
| US-5998439-A | RESPIRATORY SYSTEM DISORDERS | Hoescht Marion Roussel, Inc. (US) | 1999-12-07 | — | — | US | disclosed |