Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 16/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690780 | 0.91 | EGLN1 (0.77) | EGLN1LMNAPOLBALDH1A1 | |
| SCHEMBL2206131 | 0.89 | EGLN1 (1.00) | EGLN1LMNAPOLBALDH1A1 | |
| SCHEMBL7691442 | 0.86 | EGLN1 (0.77) | EGLN1LMNAPOLBALDH1A1 | |
| SCHEMBL7698201 | 0.85 | EGLN1 (0.76) | EGLN1LMNAPOLBALDH1A1 | |
| SCHEMBL2200760 | 0.85 | EGLN1 (1.00) | EGLN1ALDH1A1 | |
| SCHEMBL2204239 | 0.84 | EGLN1 (0.83) | EGLN1ALDH1A1 | |
| SCHEMBL7957338 | 0.83 | EGLN1 (0.73) | EGLN1LMNAPOLBALDH1A1 | |
| SCHEMBL4060463 | 0.83 | EGLN1 (0.57) | EGLN1LMNAPOLB | |
| SCHEMBL7965479 | 0.82 | EGLN1 (0.72) | EGLN1ALDH1A1 | |
| SCHEMBL7692437 | 0.82 | EGLN1 (0.71) | EGLN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | claimed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | claimed |
| US-6211376-B1 | HERPES VIRUS, CYTOMEGALO VIRUS, VARICELLA-ZOSTER VIRUS,EPSTEIN-BARR VIRUS | PHARMACIA & UPJOHN COMPANY | 2001-04-03 | — | — | US | disclosed |