Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250821 | 0.97 | TSHR (0.44) | TSHRFAAHTRPV1THRBDNM1 | |
| SCHEMBL17582709 | 0.97 | TSHR (0.44) | TSHRFAAHTRPV1THRBDNM1 | |
| SCHEMBL7329421 | 0.97 | TSHR (0.44) | TSHRFAAHTRPV1THRBDNM1 | |
| SCHEMBL5357146 | 0.92 | TSHR (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL15921186 | 0.80 | — | — | |
| SCHEMBL11146562 | 0.80 | TSHR (0.42) | TSHRFAAHTRPV1THRBDNM1 | |
| SCHEMBL9785660 | 0.80 | TSHR (0.42) | TSHRFAAHTRPV1THRBDNM1 | |
| SCHEMBL8976924 | 0.80 | TSHR (0.42) | TSHRFAAHTRPV1THRBDNM1 | |
| SCHEMBL7147029 | 0.80 | TSHR (0.42) | TSHRFAAHTRPV1THRBDNM1 | |
| SCHEMBL16909645 | 0.80 | TSHR (0.42) | TSHRFAAHTRPV1THRBDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6261359-B1 | SOLUBLE CHROMOPHORES | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-17 | — | — | US | disclosed |
| US-4587068-A | SOLVENT-FREE | MATERIALS RESEARCH CORPORATION (US) | 1986-05-06 | — | — | US | disclosed |