Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | EBP | Q15125 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11482522 | 0.98 | KMT2A (0.59) | KMT2APOLBTSHRPTPN1EBP | |
| SCHEMBL7952996 | 0.98 | KMT2A (0.59) | KMT2APOLBTSHRPTPN1EBP | |
| SCHEMBL7956543 | 0.95 | KMT2A (0.66) | KMT2APOLBTSHRPTPN1EBP | |
| SCHEMBL7959643 | 0.91 | NPC1 (0.65) | KMT2APOLBTSHRPTPN1NPC1 | |
| SCHEMBL18554186 | 0.86 | KMT2A (0.62) | KMT2APOLBTSHRPTPN1EBP | |
| SCHEMBL248401 | 0.86 | KMT2A (0.66) | KMT2APOLBTSHRPTPN1EBP | |
| SCHEMBL11482525 | 0.85 | KMT2A (0.64) | KMT2APOLBTSHRPTPN1EBP | |
| SCHEMBL14625066 | 0.85 | KMT2A (0.64) | KMT2APOLBTSHRPTPN1EBP | |
| SCHEMBL7952997 | 0.85 | KMT2A (0.64) | KMT2APOLBTSHRPTPN1EBP | |
| SCHEMBL8930342 | 0.85 | MAPT (0.64) | KMT2APOLBTSHRPTPN1EBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| CN-1262685-A | Naphthyridine derivatives | OTSUKA PHARMA CO LTD (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |