Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7966263 | 0.99 | AVPR2 (0.33) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7476203 | 0.94 | AVPR2 (0.33) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7480419 | 0.94 | AVPR2 (0.33) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7966823 | 0.94 | AVPR2 (0.34) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7966391 | 0.94 | AVPR2 (0.33) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7968982 | 0.94 | AVPR2 (0.33) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7478318 | 0.94 | AVPR2 (0.34) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7483616 | 0.94 | AVPR2 (0.34) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7487406 | 0.93 | AVPR2 (0.34) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7965096 | 0.93 | AVPR2 (0.34) | AVPR2AVPR1ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316482-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME, HEPATOCIRRHOSIS, HYPONATREMIA, HYPOKALEMIA, DIABETIC, CIRCULATION DISORDER, CEREBROVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |