Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 9/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.51 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955120 | 1.00 | PDE4B (0.55) | PDE4BPDE4DPDE5A | |
| SCHEMBL7957454 | 0.89 | PDE4B (0.53) | PDE4BPDE4DPDE5A | |
| SCHEMBL7957448 | 0.89 | PDE4B (0.53) | PDE4BPDE4DPDE5A | |
| SCHEMBL7961724 | 0.89 | PDE4B (0.55) | PDE4BPDE4DPDE5A | |
| SCHEMBL7962094 | 0.89 | PDE4B (0.53) | PDE4BPDE4DPDE5A | |
| SCHEMBL7961719 | 0.89 | PDE4B (0.55) | PDE4BPDE4DPDE5A | |
| SCHEMBL7962099 | 0.89 | PDE4B (0.53) | PDE4BPDE4DPDE5A | |
| SCHEMBL7959119 | 0.88 | PDE4B (0.56) | PDE4BPDE4DPDE5A | |
| SCHEMBL7959121 | 0.88 | PDE4B (0.56) | PDE4BPDE4DPDE5A | |
| SCHEMBL7957171 | 0.86 | PDE4B (0.53) | PDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326379-B1 | ERECTILE DYSFUNCTION; CARDIOVASCULAR DISORDERS | BRISTOL-MYERS SQUIBB CO. | 2001-12-04 | — | — | US | disclosed |