Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 6/20 | 0.48 |
| ▸ | ACHE | P22303 | 6/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 9/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959796 | 0.98 | BCHE (0.50) | IDO1BCHEACHECHRM2CHRM1 | |
| SCHEMBL7956419 | 0.95 | IDO1 (0.53) | IDO1BCHEACHETAAR1ABCB1 | |
| SCHEMBL4602231 | 0.88 | IDO1 (0.56) | IDO1BCHEACHETAAR1ABCB1 | |
| SCHEMBL2096449 | 0.86 | SMN1; SMN2 (0.46) | BCHEACHEABCB1SMN1; SMN2CYP3A4 | |
| SCHEMBL16599934 | 0.83 | IDO1 (0.51) | IDO1BCHEACHETAAR1ABCB1 | |
| SCHEMBL3655669 | 0.81 | IDO1 (0.53) | IDO1BCHEACHETAAR1ABCB1 | |
| SCHEMBL1941923 | 0.81 | IDO1 (0.53) | IDO1BCHEACHETAAR1ABCB1 | |
| SCHEMBL8193133 | 0.81 | IDO1 (0.53) | IDO1BCHEACHETAAR1ABCB1 | |
| SCHEMBL5798261 | 0.81 | IDO1 (0.53) | IDO1BCHEACHETAAR1ABCB1 | |
| SCHEMBL3166142 | 0.80 | IDO1 (0.60) | IDO1BCHEACHETAAR1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245779-B1 | ANALGESICS; ANTIINFLAMMATORY AGENTS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2001-06-12 | — | — | US | disclosed |
| EP-0997463-A1 | NAPHTHYRIDINE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-05-03 | — | — | EP | disclosed |