Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | SSTR5 | P35346 | 9/20 | 0.45 |
| ▸ | SSTR3 | P32745 | 5/20 | 0.41 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.41 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7955271 | 1.00 | NT5E (0.51) | NT5ESSTR5SSTR3SSTR2SSTR1 | |
| SCHEMBL7955867 | 0.91 | NT5E (0.61) | NT5ESSTR4HPSE | |
| SCHEMBL7955866 | 0.91 | NT5E (0.61) | NT5ESSTR4HPSE | |
| SCHEMBL7962175 | 0.89 | NT5E (0.51) | NT5E | |
| SCHEMBL7962174 | 0.89 | NT5E (0.51) | NT5E | |
| SCHEMBL7955504 | 0.88 | NT5E (0.55) | NT5ESSTR5SSTR3SSTR2SSTR1 | |
| SCHEMBL7962382 | 0.88 | NT5E (0.52) | NT5ESSTR5SSTR3SSTR2SSTR1 | |
| SCHEMBL7962386 | 0.88 | NT5E (0.52) | NT5ESSTR5SSTR3SSTR2SSTR1 | |
| SCHEMBL7959453 | 0.88 | NT5E (0.55) | NT5ESSTR5SSTR3SSTR2SSTR1 | |
| SCHEMBL7955508 | 0.88 | NT5E (0.55) | NT5ESSTR5SSTR3SSTR2SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| EP-0819135-B1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |
| CN-1185786-A | Sugar-modified cytostatics | BAYER AG (DE) | 1998-06-24 | — | — | CN | disclosed |